The Readers Response To The Novel Essay Example for Free

The Readers Response To The Novel Essay Written by Mary Shelley in 1816, Frankenstein is a novel that conveys several messages and themes. It was written at a time of social and political upheaval: the incredible advances in science and movements in art and culture were changing the way people lived dramatically. For example, the use of electricity, the French Revolution and the Romantic Movement, were leading people to have totally radical, bohemian lifestyles. Shelley allowed these revolutionary ideas to move and inspire her, enabling her to write one of the most remarkable and intriguing pieces of literature in the world. In the novel, Shelley uses three narrators: Robert Walton; Victor Frankenstein; and the monster, or modern Prometheus, as he was intended to be. The purpose of this essay is to explore what effect this has on our response to the novel overall. I shall do this by explaining how they affect our understanding of the main themes of the novel; the complex time and structure; and the narrators as characters. Mary Shelleys classic novel discusses three major themes: ambition and its consequences; the importance of family; and community and isolation. Victors horrific tale shows how blind ambition and ruthlessness can destroy you morally and physically. This happens to Victor as he loses everything dear to him and eventually his own life. Upon hearing Victors story of death and revenge, suffering and loneliness, Walton gives up his own ambition of discovering the North Pole, realising that he has sacrificed his sister for his obsession with success. Thus he is saved before it is to late. Victor on the other hand has caused his own downfall: he becomes so obsessed with his creation that he neglects his family by refusing to go home when Elizabeth writes to him. This ultimately leads to the deaths of his family, Justine and William are killed in the monsters fit of revenge, and his suffering and loneliness begin to devour him. The theme of the importance of family is reinforced throughout the novel. From Victors idyllic childhood, My mothers tender caresses, and my fathers smile of benevolent pleasure while regarding me, are my first recollections, to the monsters grief at his fathers death, close family relationships are regarded as precious and wonderful. This may be because Shelley lost her own mother when she was very young, and used her own personal experience to inspire her. Both Walton and Victor take their relationships with their sisters for granted, sacrificing them to pursue their own dreams. Victors experience shows that you cant have both: your family and your career to flourish. This idea id introduced very early in the book, when Victors departure to university is delayed by the death of his mother from Scarlet Fever.

Hypoxia-mediated Selection of Cells with Diminished Apoptotic Potential

Cancer: Necrosis vs. Apoptosis Cancer is the second leading cause of death in humans. A cancer cell is a cell that has mutated from its original form and will often grow at a more rapid rate than normal. The body has built certain mechanisms to protect itself from these types of cells. One of the physiological processes the body uses to kill off these cells is apoptosis. Apoptosis is sometimes called "cell suicide". When the body detects that a cell's DNA has mutated and cannot be repaired, the cell will somehow trigger itself to self destruct. Up until 1972, scientists hadn't really looked carefully at how cells die. Once they did, it was apparent that two things could happen: necrosis or apoptosis. Necrosis was the term used to describe all cells that had died. However scientists have found that necrosis and apoptosis are two different processes. Necrosis is a result of outside forces acting upon a cell, causing it's destruction. Upon destruction of the cell in this manner, the internal contents of the cell are leaked into the local environment, which can be extremely harmful. In contrast, a cell dying by apoptosis does not release it's contents and potentially harm neighboring cells. Apoptosis is actually an active process within the cell. A process triggers some other process (which is not quite clear) inside the cell and tells the cell to start disassembling itself. When this happens, instead of releasing harmful chemicals into its environment, the cell is thought to send parts of itself to other surrounding cells to digest it. Roles of p53 and bcl-2 in Apoptosis The authors above and other scientists believe that the expression of the p53 gene is required for apoptosis. The p53 gene has been labeled as the tumour su... ... increases as oxygen is reduced, those cells with mutated p53 have a slower increase in death rate in hypoxic regions, compared to those cells that have normal p53 expression. This seems to point to the fact that the hypoxic regions are actually setting up a natural selection for the p53 deficient cells, and possibly other mutations resistant to death. Treatment Problems This can cause a problem when treating these cells with radiation and chemotherapy. These treatments attack the cells and attempt to destroy the DNA within the cell. This will usually cause an increase in the rate of apoptosis within the area treated. However if the cells in the area have built up a resistance to apoptosis they have built up an effective resistance to the chemotherapy and radiation. These facts could explain why the p53 gene is the most commonly mutated gene in human cancer.

Othello and O

Othello and â€Å"O† The movie â€Å"O† by Tim Blake Nelson is based on Shakespeare’s play â€Å"Othello. They both have many differences as well as similarities. The same trap is laid for the main character in both versions and the same amount of casualties happens in both final scenes. Nelson sets his story in modern time prep school, and his characters are not the adults of Shakespeare's play. Shakespeare Othello is set in the 16th century while Nelsons â€Å"O† is set I the 20th century.In Othello, the setting is in 16th century Cyprus during a war with the Turkish Empire. The language used in respectful and nice compared to â€Å"O†. Brabantio calls Othello to the summit and questions him what sorcery he has used to take his daughter Desdemona away from him. Desdemona denies the fact that Othello used any sorcery and says that there love is true and that she left her father for her husband and he left his family for her mother. In this play De sdemona is married to Othello.Iago’s reasons of jealousy are that Othello promoted Cassio to Lieutenant instead of him and that there’s a well-known rumor that Othello has slept with his where the truth hasn’t been brought to light. Nobody is aware of neither Iago’s nor Rodrigo’s intentions. Othello has epilepsy and Iago doesn’t help until Cassio walks in. Desdemona is slapped by Othello and no one can believe that the well-known respected general would do such a thing. Othello makes Iago his blood brother and Iago tells him to kill Desdemona and he will kill Cassio for him.But Iago Sends Rodrigo instead of doing it himself to kill Cassio but fails wring and Rodrigo gets injured and runs away than Iago comes and stabs Cassio in the leg then goes and kills Rodrigo. When Othello kills Desdemona, Emilia comes in and see’s that Desdemona is dead and Othello confessed to his crime so Emilia cries out murder where everyone came in including Iago where he starts to argue with Emilia and tells her to be quite but she doesn’t listen and then he tells her to go home but she doesn’t go therefore disrupting him and then she tells the truth about the handkerchief so stabs and kills her and then runs away.When Othello realizes what he has done he stabs himself and lays on her and kisses her in the lips as he dies. In â€Å"O†, the setting is in the modern-era prep school where instead of a war being fought it’s a series of basketball games. In this movie foul disrespectful language is used compared to Othello. Iago feels that his father Duke loves Oden more than he loves him so he tries so hard to win his father’s love from Oden.When Brandy calls Oden to the main office he accuses Oden of forcing Desy and then accuses him of using drugs again because of his skin color. Then Duke calls for Desy and she tells her father that they been together a few months before he even found out and that ità ¢â‚¬â„¢s none of his business. Oden gets injured during a game while in Othello he doesn’t. Desy is more aware of Iago and Oden beats up Rodger because he is aware of Rodger. Oden is so jealous and angry that he attacks Hugo and then storms out the court.Instead of Oden having epilepsy he takes cocaine instead. The scene on Othello where Othello slaps Desdemona is different in the fact that instead Oden after he takes cocaine and is hyped up he enters the court for the slam-dunk contest and breaks the backboard which everyone one loves at first until he breaks the backboard completely and takes off the rim slams it and disrespects a kid and pushes him off to the side where the whole audience, crowd was shocked because they couldn’t believe what they seen.Instead of using a knife, Rodger shoots Hugo in the leg and then Hugo gets frustrated and kills Rodger and tries to make it look like and accident then Brandy came and Hugo asked for her help to call the cops but she g ot scared and ran away. Hugo instead of stabbing Emily he shoots her and runs away. When oden realizes what he has done and knows everything he shoots himself in the deck of the house and lay’s on the couch away from Desy. In both the play and the movies Iago and Hugo are fueled by jealousy.The same trap is set in place for the characters and the same amount of deaths happen in the end of the movie/play. In both Emalia/Emily steal the scarf for Iago/Hugo which leads them to having sexual intercourse. Both Desdemona/Desy believe they have misplaced the scarf given to them by Othello/Oden. In both the play and the movie Iago/Hugo is very envious of Othello/Hugo because everyone respects and admires him. Othello is the only black person in the play and so is Oden in the movie.Othello/Oden promotes/chooses Cassio/Mike instead of Iago/Hugo. In both plays Iago/Hugo build hatred/jealousy against Iago/Hugo which starts the whole plot of both the movie and play. Iago/Hugo betrays Othe llo/oden and does not care who gets hurt in the process of destroying Othello/Hugo. Iago/Hugo does not do everything alone he is helped out by Rodrigo/Rodger which in both the play and the movie is secretly in love with Desdemona/Desy. Iago/Hugo and Rodrigo/Rodger make Othello/Oden believe Desdemona/Desy has been cheating on im with Cassio/Mike. When Iago/Hugo kills Emilia/Emily he runs away but is later caught by other men and when Othello/Oden asks Iago/Hugo why has he done all of this to him and Iago/Oden replies that he doesn’t need to know and from now on he will not say another word. After Othello/Oden realize t=what they have done he kills himself. Both the play Othello by Shakespeare and â€Å"O† by Blake nelson are wonderful and have a great story line that catches the viewers’ attention.They both have a tragic story and a very sad ending with high body counts. Both the play and movie have everyday problem and issues that still happen even today that pr oves Shakespeare is a very intelligent man. It’s a sad thing that these problems were around for many centuries and still exist today. Since the movie was based on the play they are very similar except that the movie is set in a modern time period. They both are very great and I recommend them both.

Special Education, Social Justice, And Effective Learning...

As we grow in education, it always seems as in there is someone that is left behind. Educators need to be able to reach out as many students as possible, but some may argue that it does not feel this way. Often, students with special education needs are considered to be too difficult to teach, or simple just a â€Å"lost cause.† The way we interact and care for all students not only shows in each student, but it shows in the impact it has on the community as a whole. Keywords: special education, social justice, †¦ Introduction Students with special needs need deserve the same education general education students are presented with. The philosophy of â€Å" Disability Inclusion† concentrates on creating a safe, loving, and effective learning environment for students who suffer from physical, learning, and behavioral disabilities. When a student with disabilities is placed in the same environment as a non-disabled student, the results show wonderful improvement. When we are able to discover the strength of the student we are able to see just how much the student can improve in an inclusion classroom. Disability Inclusion not only sets a new beginning for an equal education of special education students, but it allows for more interaction with the child, and a more hands-on assessment. To first define the Disability Inclusion theory, we need to understand the meaning behind these two terms. According to the National Center for Learning Disabilities, they defined a learningShow MoreRelated Mainstreaming : The Influence Of Inclusion Based Education1586 Words   |  7 PagesMainstreaming: The Influence of Inclusion-Based Education According to the Foundation for People with Learning Disabilities, 89% of children with moderate learning difficulties, 24% of children with severe learning difficulties and 18% of children with profound multiple learning difficulties are educated in mainstream schools. A practice so prevalent must surely be effective. 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